glutathione s transferase a1 S-transferase and MRP1 form an integrated system involved in the storage and transport of dinitrosyl–dithiolato iron complexes in cells Glutathione Transferase - an overview

Targeting USP8 inhibits O-GlcNAcylation of SLC7A11 to promote ferroptosis of hepatocellular carcinoma via stabilization of OGT

The concentration and quality of the total RNA were assessed using the Quant-it RiboGreen RNA assay (Thermo Fisher Scientific, #R11490) and the RNA 6000 Pico chip (Agilent Technologies), respectively

For instance, the depletion of short-chain fatty acids (SCFAs) promotes the polarization of M1 macrophages, which drives intestinal inflammation [36]

Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells

Stable Isotope Tracing (13C-Met) : Tracking methionine metabolic flux showed a 30% reduction in methionine-to-SAM conversion efficiency in the cachexia model, with no compensatory upregulation of the transsulfuration pathway (generating Cys and GSH)