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Malagelada C, Jin ZH, Greene LA (2008) RTP801 is induced in Parkinsons disease and mediates neuron death by inhibiting Akt phosphorylation/activation

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Along with strong GH release, it produces significant appetite stimulation through ghrelin receptor activation, mild to moderate cortisol and prolactin elevation, and the most intense hunger response of any peptide in this class

Intranasal administration is valued as a non-invasive means of both systemic and local administration with good bioavailability, rapid onset, and targeted effects on the central nervous system [13, 14]