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New England Journal of Medicine, 368(2), 149-160

Martinowich K, Hattori D, Wu H, Fouse S, He F, Hu Y et al (2003)

Comparisons of nitrates relative to nitroglycerin: isosorbide dinitrates dinitrate is degraded at 1/6 the rate Isosorbide dintrate has long acting metabolites, isosorbide-2-mononitrate and isosorbide-5-mononitrate, with half-lives of 2 to 5 hours

A potential limitation of this work was that toxicity tests were conducted at ambient rather than elevated pressures, although (as discussed in Section 6.7) modeling efforts have shown that elevated pressures result in reductions in hydrocarbon toxicity (Paquin et al., 2018)

He tried the unflavored creatine, and felt that it does taste truly unflavored, earning it a 5 out of 5 for flavor