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[DOI] [PMC free article] [PubMed] [Google Scholar] 76.Kannan R., Stolz A., Ji Q., Prasad P.D., Ganapathy V

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Dihydrolipoic acid (DHLA), the reduced form of lipoic acid, restores these antioxidants by reducing their oxidized forms, maintaining redox balance through antioxidant regeneration

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Thus, G6PD deficiency can cause the destruction of red blood cells through a build-up of oxidants in certain situations.[ref] NADPH is important in maintaining homeostasis in cells in several ways