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The immunogenic profiles of metE formulated in the two different adjuvants differed, with metE -AS01 inducing antigen-specific IFN-, TNF-, IL-2, IL-17, IgG1 and IgG2a-c, while metE -AddaS03 induced TNF-, IL-2, IL-17, IL-4, IgM, IgG1, IgG2b

In this case, proximal motor roots can be unexpectedly block with a variable extension of myelitis at the level of lumbar infusion producing a complete paresis in lower limbs (paraparesis) with a lower abdomen level of sensory loss together with urinary dysfunction

IGF-1 establishes a negative feedback loop in inhibiting the secretion of growth hormone

Tomasova, L., Konopelski, P

Devaux et al, 2020)