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doi: 10.1074/jbc.M110.115097 132 SahuM.KarR

3.2.2 Photoaging theory The skin, which covers approximately 1.52 m 2 of the human body, serves as its primary physiological barrier (Xu et al., 2023) and encounters external stimuli such as UVR, smoke, and harmful pollutants (Ge et al., 2024)