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Causes of varicoceles may include: Lifestyle factors, such as smoking Oxidative stress Inability to make or have glutathione (an important our master antioxidant) Hormonal imbalance Hyperthermia Exposure to toxic substances Testicular blood flow Venous pressure Reactive oxygen species or ROS (free radicals) Genetic factors Treatments for Varicoceles Oftentimes, varicoceles dont require treatment, but in the event of pain, infertility, or testicular atrophy, they may require varicoceles repair procedures