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The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance PMID: 25738459 Cell Metab

doi: 10.1084/jem.20210518 6 XuSMinJWangF

Other studies have also shown that HIF-1 regulates the expression of certain cytochrome components directly and also regulates specific microRNAs that in turn regulate the expression of components of the electron transport chain [10,39,40]