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Together, our data suggest that secondary sulfonylurea failure may reflect islet cell reprogramming and loss of -cell identity, rather than simple -cell exhaustion To view or add a comment, sign in Clinical Efficacy of Second-Generation Tetracyclines as First-Line Systemic Agents for Gingival Lichen Planus In a recent JDD report of 254 biopsyconfirmed patients whose erythematous or erosive gingival oral lichen planus failed topical therapy, a 2month course of doxycycline or minocycline (100 mg twice daily), given alongside topical agents, produced clinical improvement in about 61% of patients

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[9] Because B vitamins are water-soluble, excess amounts are excreted in urine, which can lead to a noticeable change in urine color

Fu J, Zhao SD, Liu HJ, Yuan QH, Liu SM, Zhang YM, et al