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The researchers created two main variants of CAHS D proteins, a 2X Linker Variant and a linker region (LR) variant

Maiti MK, Sahu NP, Sardar P, Garg CK, Varghese T, Shamna N, Deo AD

In mice, in particular, palmitate-induced phosphorylation of DDX1 displaces it from the preproinsulin mRNA and suppresses insulin biosynthesis, hence providing a direct link between hyperlipidaemia and insulin deficiency [38]