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Signs of B12 Deficiency to Watch For Breastfeeding mothers should be aware of symptoms that may indicate a B12 deficiency, such as persistent fatigue, weakness, tingling in the hands or feet, memory problems, or mood changes

In individuals with pre-existing gastrointestinal conditions such as inflammatory bowel disease, coeliac disease, or irritable bowel syndrome, introducing any new supplement may temporarily affect bowel habits as the digestive system adapts

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In clinical studies, participants taking Retatrutide experienced up to 24% weight loss over 48 weeks, more than observed with current GLP-1 treatments

Taken together, these results suggest high selectivity of the small molecule 5-amino-1MQ analogue at pharmacologically relevant concentrations to NNMT-inhibition