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The FcRn mediates both efflux (from the brain to the bloodstream) and potentially influx (from the bloodstream to the brain) transcytosis of IgG, which may have significant implications for the delivery of drugs to the CNS [178]

ZIMMERING, S., MASON, J.M., VALENCIA, R., & WOODRUFF, R

10.1080/10408444.2022.2128718 106 KaurG.PrakashA

However, the potential effects of the Set7/9-mediated methylation of FOXO3 on its target antioxidant genes, MnSOD and CAT, were not investigated in this study

In the past couple decades, investigations into PD pathology have revealed some distinct features, such as iron accumulation, lipid peroxidation, glutathione depletion, CoQ10 deficiency, glutathione peroxidase (Gpx4) reduction, mitochondrial lesions, among others 7