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131 In general, gene therapy can be categorized into gene augmentation and gene silencing approaches based on the nature of the effect on genetic activity

Phencyclidine was reported to acutely induce a reduction of glutamate levels accompanied by glutamine accumulation (without changes in the total content of glutamate plus glutamine, called Glx) in the rat prefrontal cortex [64]

Despite the extensive research into amyloid (A) deposition and tau protein hyperphosphorylation (p-tau), an effective treatment to stop or slow down the progression of neurodegeneration is missing