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The binding mode for 1j permits the formation of strong hydrophobic interactions within the apolar pocket surrounding the quinolinium N1-atom, consisting of Tyr20, Tyr204, Tyr242, Leu164, Ala198, and Ala247 residues (hydrophobic residues highlighted by red hashed lines,FIG

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This risk-based approach determines what levels of treatment are required to reduce the concentrations of pathogens in a source water (including wastewater) down to acceptable levels for drinking

However, we disagree and note that the Overall Hospital Quality Star Rating has always been intended to be an accessible, easily interpreted summary of available hospital quality information