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How B12 Deficiency Is Diagnosed and Monitored on the NHS Diagnosis is primarily via serum B12 blood testing, with BOMSS recommending routine monitoring at 3, 6, and 12 months post-operatively and annually thereafter

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Last reviewed: May 29, 2026

Only about 30 humans have ever been studied, all by one doctor, with no control groups

In comparison, oral B12 supplements must first pass through the digestive system