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Although GHK-Cu has a history of safe use, certain populations are better off avoiding it.3 11 These include: Anyone under the age of 18: We dont yet know if copper peptides can have an adverse effect on young people

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It is placed under the tongue or between the cheek and gum, where it dissolves slowly over 15 to 30 minutes, allowing the peptide to absorb through the oral mucosa into the bloodstream

The initiation of vascularization at an earlier stage of wound healing can result in a faster rate of wound closure

If supplementing copper through GHK-CU, ensure dietary zinc is adequate