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Data availability The mass spectrometry proteomic data generated in this study have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PXD074092

193 These studies prove that PRMTs are potential targets for cancer therapy, and several PRMTs inhibitors are currently in clinical trials (Table 1)

On the basis of parameters average latency to find the platform and the number of successful attempts, the mice were subdivided into two groups: high cognitive performance in the MWM (HP group) and low cognitive performance in the MWM (LP group)