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Description

Increased sensitivity to alcohol, medications, or environmental exposures

Microglia resist the onset and progression of AD by degrading A and tau

Warszawa, Poland: 2019

NNMT inhibition as a therapeutic strategy has been explored in industry pharmaceutical pipelines (including a Pfizer program for non-alcoholic fatty liver disease that was reportedly discontinued in early clinical development), but no NNMT inhibitor has reached regulatory approval to date