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J Environ Sci Health Part B

Paul, MN, US

Canagliflozin significantly inhibits inflammatory factor expression, including cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase, exerting cardioprotective effects by regulating inflammation and ferroptosis through the AMP-activated protein kinase (AMPK) pathway (83)

J Eur Acad Dermatol Venereol 26:4751 Chamcheu JC, Adhami VM, Esnault S, Sechi M, Siddiqui IA, Satyshur KA, Syed DN, Dodwad SM, Chaves-Rodriquez MI, Longley BJ, Wood GS, Mukhtar H (2017) Dual Inhibition of PI3K/Akt and mTOR by the dietary anti-oxidant, delphinidin, ameliorates psoriatic features in vitro and in an imiquimod-induced psoriasis-like disease in mice