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They are two different design strategies

By targeting adipose (fat) tissue, AOD-9604 aims to boost metabolism and break down stored fat , potentially helping with weight loss while avoiding significant impacts on blood sugar or muscle

While some patients receive these shots at a clinic, many are advised by their healthcare providers to self-inject at home for convenience and consistency

The motivation to eat well follows from the physical improvement, rather than the peptide suppressing hunger signals directly

However, the efficacy of small molecule inhibitors targeting NNMT remains uncertain due to their lack of selectivity and low metabolic stability (Iyamu and Huang, 2021)