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Studies have shown that under hyperoxic conditions, mitochondria in pulmonary epithelial cells exhibit significant structural and functional abnormalities, with a marked decrease in the activity of respiratory chain complexes I and IV, inhibition of oxidative phosphorylation, and alterations in mitochondrial morphology, such as vacuolization and cristae fragmentation (Garcia et al., 2021

For example, in the extensor digitorum longus, the force deficit following stretches that reached 40% beyond optimal fiber length appeared to be reduced

Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats

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