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To this end, PC12 cells were subjected to high concentration (0.5 mM) of 6-hydroxy-dopamine (6-HO-DA) for 24 hour, in the presence of 0.3 mM or 0.8 mM of compounds A-D or 1 nM of reduced glutathione (GSH) a natural antioxidant, as shown in the front row of FIG