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dressings are changed as prescribed by the surgeon, usually on the second through the fifth postoperative days in postsurgical wounds

10.1371/journal.pone.0162590 45 Lovric-BencicM.SikiricP.HanzevackiJ

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Combining the easy scale-up of the DEF-CS single-cell culture system for iPSCs, the highly efficient DE induction by the STEMdiff Definitive Endoderm kit, the robust hepatic specification guided by DMSO and HGF, and the hepatocyte maturation promoted by DEX, dihexa and OSM, this improved method may allow for robust generation of homogeneous functional hepatocytes from human stem cells and opens up new possibilities for drug discovery, hepatotoxicity studies and liver regenerative therapy