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While taking a daily low-dose aspirin (81 mg) before your flu vaccine may be OK, aspirin taken at a higher dose for pain relief (650 mg) could decrease your flu shot response

In fact, despite Omicron escape from nAbs induced by vaccine or previous infection, infected individuals have shown mild disease, indicating a possible involvement of T cells in disease modulation 51

M., et al., 2019

The reduction in intracellular cholesterol concentration induces an increased expression of low-density lipoprotein receptors (LDL-Rs) on the surface of the hepatocytes, which results in increased uptake of low-density lipoprotein cholesterol (LDL-C) from the blood and a decreased plasma concentration of LDL-C and other apoB-containing lipoproteins, including triglycerides (TG)-rich particles

Formulation and delivery remain challenges