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As discussed in the CY 2025 PFS proposed rule, this information is also relevant to the alternative quality performance standard under which ACOs that fail to meet the quality performance standard to qualify for the maximum sharing rate, but that achieve a quality performance score equivalent to or higher than the 10th percentile of the performance benchmark on at least one of the four outcome measures in the APP Plus quality measure set, may be eligible to share in savings on a sliding scale, as discussed in the current 425.512(a)(4)(ii) (89 FR 61866)

HO-1 and the HO system in general are thought to play a critical role in cellular homeostasis where the presence of complementarity or overlap between the arms of action could result in some degree of redundancy that can help to ensure the induction of HO mediated critical effects

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Noboru Yonamine, Glenn Ohigashi, Tim Ho, Sen

Funding The author(s) declare financial support was received for the research, authorship, and/or publication of this article