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The overall reaction is: 6 Glucose 6-phosphate + ATP 6 Ribose 5-phosphate + ADP + H + Under these metabolic conditions, there is a functional interplay between glycolysis and the non-oxidative phase of the pentose phosphate pathway, with the latter running in the direction of ribose 5-phosphate synthesis

When researchers looked at all participants regardless of whether they stuck with the medication, the numbers were similar: 11.5% versus 3%

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