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A study of mitochondria in old spontaneously hypertensive rats

After treatment with shRNA lentivirus and NAC or Fer-1, we chose 8 PDOs at similar sizes to observe

Metabolic flexibility Although glutamine is the primary carbon source for the TCA cycle in some cancer cells, replenishment of TCA cycle intermediates using alternative anaplerotic substrates reduces bioenergetic stress, thereby enabling resistance to inhibition of glutamine metabolism

V., Piperno R., and Hrelia S., Traumatic Brain Injury and NADPH Oxidase: A Deep Relationship, Oxidative Medicine and Cellular Longevity 2015 (2015): 370312, 10.1155/2015/370312

Both ferroptosis inducers and inhibitors may reduce inflammation and then inhibit joint damage