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Large-scale CRISPR screen of LDLR pathogenic variants

Proximity Interactions Among Centrosome Components Identify Regulators of Centriole Duplication

doi: 10.1007/s12272-020-01273-8 44 HassanniaBWiernickiBIngoldIQuFVan HerckSTyurinaYYet al

Another limitation observed was that BA-LRA scores were biased toward P450-mediated bioactivation compared to drugs that form reactive CoA-thioesters or unstable acyl-glucuronides