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Interestingly, our data suggest that decreased GPX4 protein levels are mediated, at least in part, by autophagy-dependent degradation

11 To gain further insight into GSH homeostasis, using high-resolution mass-spectrometry metabolic profiling, we documented decreased levels of both sulfur and non-sulfur amino acids involved in GSH-synthesis (serine, betaine, glutamate, cysteine and methionine) as well as metabolites related to GSH-metabolism (-glutamyl-valine and -glutamyl-leucine) in arterial cord blood