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A recent study further demonstrated that WBP1-deficient CRC cells regained sensitivity to 5-FU following the restoration of mitochondrial function [65], reinforcing a causal link between mitochondrial homeostasis and drug responsiveness

To distinguish between monomeric and assembled states, we determined the critical aggregation concentrations of compounds 1 and 2 to be 59.4 M and 114.7 M, respectively (Supplementary Fig

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