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Description

In severe MASLD, functional analysis revealed increases in fatty acid degradation and flavonoid biosynthesis, and decreases in pyrimidine metabolism, steroid biosynthesis, folate biosynthesis, and alanine, aspartate, glutamate metabolism

The RMSF value was maintained within a range of 0.401.60 for all ligands, with an exception observed within residues 40 and 90 of GPx4 in their binding with Lip-1, where the RMSF value increased to 0.402.8