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Description

Du Y, Li D, Chen J, Li YH, Zhang Z, Hidayat K

There are cases where patients do not need any touch-ups

This comparison indicated that the W386Y mutation, which impacts the activity of dHTC1, but not SR-1114, also does not impact CC-885 activity (Extended Data Fig

Our results showed that the contribution of the TSS pathway on de novo cysteine synthesis and GSH generation is only detectable under cystine-restricted conditions, and such function is dimmed when cystine is supplemented at supraphysiological concentrations