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We recently found that lung cancer cells that express more genes that are typically restricted to the germline (germ cell cancer genes, GC genes) repair DNA double-strand breaks more rapidly, show higher rates of proliferation, and are more resistant to ionizing radiation, compared to cells that express fewer GC genes

Finally, a longitudinal study assessing blood PFAS concentrations found increased BDNF levels in children (Yu et al., 2021), whereas a study assessing acrylamide exposure found no associations ( It seems that some metals showed a consistent association with decreasing BDNF levels during childhood and adulthood, which could increase the odds of developing neurodevelopmental alterations

Homocysteine Remethylation and Methionine Regeneration Homocysteine can be recycled into methionine through two major enzymatic pathways: Methionine synthase (MS) utilizes 5-methyltetrahydrofolate (5-MTHF) from the folate cycle as a methyl donor, requiring vitamin B12 as a cofactor

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