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If pigmentation is undesirable, reduce dosing frequency to once weekly or lower the dose to 0.5mg

FDA wystosowaa Warning Letters wobec sprzedawcw MT-II w 2007 roku, brytyjska MHRA wydaa ostrzeenie w 2008 roku

Newer slow-release formulations of niacin and combination drugs reduce incidence of flushing

This means they must be converted to L-ascorbic acid before theyre of use to the skin