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The core members of the auxin signal transduction mechanism are composed of three protein families which are used as auxin coreceptors: transport inhibitor response1/auxin signaling F-box protein (TIR1/AFB), auxin/indole-3-acetic acid transcriptional repressor (Aux/IAA) and auxin response factor (ARF) [67]

Adults should take 5 mg/day, pregnant women 6 mg/day, and lactating women 7 mg/day

Vitamin A supplementation above 5,000 IU/day causes additive hypervitaminosis A toxicity [13]

Although this classification is based on the primary sequences, the recent release of several plant genomes allowed for its correlation with the intron-exon structure of GST-encoding genes as analyzed in P

The latter is not yet targeted by approved drugs according to currently available databases and might therefore be interesting for drug repurposing efforts