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10.1161/CIRCULATIONAHA.119.040551 96

XD and YL contributed to the chemical synthesis and purity analysis of the compound

According to a recently proposed hierarchical oxidative stress model, [8, 9] a low level of oxidative stress, such as exposure to diesel exhaust products for 6 hours at a concentration of 10 to 50 g/mL, [10] leads to the activation of the transcription factor, nuclear erythroid 2 p45-related factor 2 (Nrf2), which encodes more than 200 genes

The study, led by Astrup A and Madsbad S, involved obese subjects who received different doses of Tesofensine or a placebo for 24 weeks

D.Mac GroryB.AiY.et al (2017)