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Relative mRNA expression of Gclm (p = 0.0026), Hmox1 , Nqo1 , and Slc7a11 (d) and representative immunohistochemistry of indicated proteins (e) in Gclc WT and Gclc KO tumors (n = 6 representative from 3 independent experiments)

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Investigated for effects on cell motility, cytoskeletal organization, and tissue repair endpoints in tendon, ligament, and muscle in preclinical studies

Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores

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