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This is especially helpful if your body has trouble absorbing B12 from food or supplements

10.3390/ijms19103082 81 ChiS

Ann Translational Med 9

doi: 10.1016/0003-9861(88)90188-9

5.2 Limitations of conventional topical flavonoid delivery Although certain flavonoids such as naringenin and flavanone exhibit enhanced skin permeability under inflamed or barrier-compromised conditions, their transdermal absorption remains limited in intact skin, often necessitating the use of penetration enhancers to achieve therapeutic depth (Wang et al., 2024)