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Similarly, a placebo-controlled clinical trial was conducted with 84 schizophrenia patients who received NAC orally twice daily (0.6 g) for 12 weeks

Moreover, it was postulated that the aromatic ring of the 3-homotyrosine side chain and the C-terminal phenyl ring interact and Phe550 in IRAP further stabilizes aromatic/hydrophobic packing (Barlow et al., 2020)

They are employed when oral iron supplementation is inadequate, poorly absorbed, or not tolerated and are primarily used to treat iron deficiency anemia