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doi: 10.1016/j.smim.2018.10.004 234 de LavalBMaurizioJKandallaPKBrisouGSimonnetLHuberCet al

demonstrated that SFN (25 mg/kg orally) administered to C57BL/6 mice of the AD model had an improvement in both cognitive and locomotor impairments (82)

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Additionally, the diet reduces the expression of microglial activation markers (e.g., Iba1, CD11b), mitigating neuroinflammation, with its protective effects independent of amyloid- plaque reduction, thus offering new targets for intervening in early cognitive dysfunction (Di Lucente et al., 2024)

It stimulates protein synthesis, tissue repair, and cellular regeneration