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The novel triterpenoid CDDO-Me promotes apoptosis in Gleevec-resistant chronic myeloid leukemia cells by caspase-independent mechanism

10.1136/bmjmed-2023-000554 [DOI] [PMC free article] [PubMed] [Google Scholar] 26

The coexistence of both conformations suggests the apo transporter samples a dynamic conformational ensemble, which likely includes outward conformations