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The latest findings further revealed that the HECT domain-containing ubiquitin E3 ligase HUWE1 was also an underlying protective modulator that could combat ferroptosis and abnormal iron accumulation by diminishing the amassing of TfR1, reducing the risk of ALF (Wu et al., 2022)

Stabilization of hypoxia-inducible factor-1 alleviates osteoarthritis via interacting with Per2 and resetting the circadian clock

Thus, the analysis of research papers data determines the perspective and expediency of the study of selected drugs and substances with the aim of establishing the mechanisms of neuroprotective action due to the effect on the expression of the HSP70