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This approach, which often involves applying a fraction of the standard dose, is designed to investigate the cellular or physiological responses without provoking the full-blown effects of the drug

Pediatric patients may be more susceptible to systemic toxicity from equivalent doses due to their larger skin surface to body mass ratios (see PRECAUTIONS: Pediatric Use)

When peripheral blood abnormalities are identified, the decision to further assess hematopoiesis by performing an invasive bone marrow procedure is influenced by a moderate number of quantitative findings from the CBC and a greater number of qualitative abnormalities found on inspection of the peripheral blood smear

As the balloon moves back up through the esophagus, its textured surface collects cells which can then be tested in the laboratory

of Corneille, Dictionnaire des arts et des sciences ]