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doi: 10.3389/fimmu.2022.1038650 Received 07 September 2022 Accepted 28 November 2022 Published 12 December 2022 Volume 13 - 2022 Edited by Olivier Feron, Universit Catholique de Louvain, Belgium Reviewed by Jie M

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Hyperpigmentation inside the mouth due to low B12 levels may appear as bluish or dark discoloration