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Normal methylation cycles absolutely depend upon adequate levels of vitamin B12 as well as other key nutrients such as folate, riboflavin, B6, niacin, magnesium, and zinc

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Youll need a prescription for B12 shots, so a healthcare professional can talk through any safety concerns

Acknowledgements The authors gratefully acknowledge the participation of the patients and the contribution of the investigators from five hospitals

Supportive secondary endpoints were not included in the statistical testing hierarchy and were: achievement of weight loss of 20% at week 104