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It is a reason to read it carefully and to weigh independent replication accordingly

10.1016/bs.pmch.2018.12.001 Prog

While preclinical findings are encouraging, human clinical evidence remains limited , and the compound should be viewed as a research-stage metabolic therapy rather than an established treatment for obesity or weight management

Genes encoding WRKY transcription factors, PR-proteins, a phenylalanine ammonia-lyase (PAL) and a GST were up-regulated in infected berries (Agudelo-Romero et al., Vitis ) species may resist fungal infections by accumulating secondary metabolites like stilbenoid phytoalexins (trans-resveratrols)