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Gastric emptying was assessed 2 days pre-treatment and 24 h after the dose at day 2, day 30, and day 79

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The antinociceptive impact of DSIP was negated by the opioid antagonist naloxone and was not observed in morphine-tolerant mice, suggesting that DSIP acts at the supraspinal level, possibly influencing opioid receptors [11]