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RanBP2-mediated SUMOylation promotes human DNA polymerase Lambda nuclear localization and DNA repair

My laboratory uses CRISPR/Cas9 gene editing technologies, next generation sequencing, pluripotent stem cells and mouse modeling to achieve this goal

This information could provide the translational evidence that diabetes is a critical player in PDAC patient outcome that could further corroborate the importance of monitoring diabetes, a manageable condition, in the precancer, early detection setting