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As just mentioned before, homeostats appear also to constitute important parts of signalling processes in plants (Contador-lvarez et al., Reference Contador-lvarez, Rojas-Rocco, Rodrguez-Gmez, Rubio-Melndez, Riedelsberger, Michard and Dreyer2025)

Berberine is a novel type efflux inhibitor which attenuates the MexXY-mediated aminoglycoside resistance in Pseudomonas aeruginosa

following intravenous injection, it accumulates in the lungs while decreasing distribution to other organs ( Figure 2A ), indicating a favorable safety profile (Zhang et al., 2022b)