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These findings suggest that DSIP, especially when combined with CBBBP, effectively mitigates PCPA-induced changes in sucrose preference, offering valuable insights into potential treatments for hedonistic behavior modifications in clinical settings ( The research presented in Figures 6AD explores the impact of various treatments on biochemical biomarkers associated with stress and sleep disorders, highlighting the differential efficacy of these interventions in modulating serum levels of melatonin, serotonin, dopamine, and glutamate among different groups

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The JAK family comprises JAK1, JAK2, JAK3, and tyrosine kinase 2 (TYK2)

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Discontinuation due to adverse events was about 4% across all dose groups